Spider-Man: No Way Home
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Peter Parker asks Doctor Strange to cast a spell to make the world forget his secret identity. The spell tears open the multiverse, pulling in villains and Spider-Men from other worlds.
The spell gone wrong is the clearest on-screen sign the multiverse is cracked open, feeding directly into Multiverse of Madness.
See Doctor Strange in the Multiverse of MadnessSkipping these means missing the setup this entry pays off. See the Watch Order page for the full picture.
1) Eddie Brock is pulled back to his universe, leaving a symbiote drop behind. 2) The final swing is a rooftop shot that resets Peter to being a friendly neighborhood hero.
No Way Home: The Multiverse's Greatest Hits
Three Spider-Men, five villains, and one broken spell that changed Peter Parker's life forever.